diff --git a/packages/nuqs/src/parsers.ts b/packages/nuqs/src/parsers.ts
index 9a94681b2..7871c036e 100644
--- a/packages/nuqs/src/parsers.ts
+++ b/packages/nuqs/src/parsers.ts
@@ -14,8 +14,10 @@ export type Parser<T> = {
 
   /**
    * Render the state value into a query string value.
+   *
+   * Return `null` to remove the query parameter from the URL.
    */
-  serialize?: (value: T) => string
+  serialize?: (value: T) => string | null
 
   /**
    * Check if two state values are equal.
@@ -94,7 +96,7 @@ export type ParserBuilder<T> = Required<Parser<T>> &
  * you can pass to one of the hooks, making its default value type safe.
  */
 export function createParser<T>(
-  parser: Require<Parser<T>, 'parse' | 'serialize'>
+  parser: Require<Parser<T>, 'parse'>
 ): ParserBuilder<T> {
   function parseServerSideNullable(value: string | string[] | undefined) {
     if (typeof value === 'undefined') {
@@ -117,6 +119,7 @@ export function createParser<T>(
 
   return {
     eq: (a, b) => a === b,
+    serialize: String,
     ...parser,
     parseServerSide: parseServerSideNullable,
     withDefault(defaultValue) {
@@ -401,12 +404,11 @@ export function parseAsArrayOf<ItemType>(
     },
     serialize: values =>
       values
-        .map<string>(value => {
-          const str = itemParser.serialize
-            ? itemParser.serialize(value)
-            : String(value)
-          return str.replaceAll(separator, encodedSeparator)
+        .map<string | null>(value => {
+          const str = (itemParser.serialize ?? String)(value)
+          return str?.replaceAll(separator, encodedSeparator) ?? null
         })
+        .filter(value => value !== null)
         .join(separator),
     eq(a, b) {
       if (a === b) {
diff --git a/packages/nuqs/src/serializer.ts b/packages/nuqs/src/serializer.ts
index 272c05b18..099b1feca 100644
--- a/packages/nuqs/src/serializer.ts
+++ b/packages/nuqs/src/serializer.ts
@@ -63,7 +63,12 @@ export function createSerializer<
       ) {
         search.delete(urlKey)
       } else {
-        search.set(urlKey, parser.serialize(value))
+        const serialized = parser.serialize(value)
+        if (serialized === null) {
+          search.delete(urlKey)
+        } else {
+          search.set(urlKey, serialized)
+        }
       }
     }
     return base + renderQueryString(search)
diff --git a/packages/nuqs/src/update-queue.ts b/packages/nuqs/src/update-queue.ts
index 12c6890df..f50ec7c7a 100644
--- a/packages/nuqs/src/update-queue.ts
+++ b/packages/nuqs/src/update-queue.ts
@@ -37,7 +37,7 @@ export function resetQueue() {
 export function enqueueQueryStringUpdate<Value>(
   key: string,
   value: Value | null,
-  serialize: (value: Value) => string,
+  serialize: (value: Value) => string | null,
   options: Pick<
     Options,
     'history' | 'scroll' | 'shallow' | 'startTransition' | 'throttleMs'