diff --git a/multichain-testing/ava.fusdc.config.js b/multichain-testing/ava.fusdc.config.js
new file mode 100644
index 000000000000..2e76acc2d195
--- /dev/null
+++ b/multichain-testing/ava.fusdc.config.js
@@ -0,0 +1,11 @@
+export default {
+  extensions: {
+    ts: 'module',
+  },
+  require: ['@endo/init/debug.js'],
+  nodeArguments: ['--import=tsimp/import'],
+  files: ['test/fast-usdc/**/*.test.ts'],
+  concurrency: 1,
+  serial: true,
+  timeout: '125s',
+};
diff --git a/multichain-testing/ava.main.config.js b/multichain-testing/ava.main.config.js
new file mode 100644
index 000000000000..b3719a2569e4
--- /dev/null
+++ b/multichain-testing/ava.main.config.js
@@ -0,0 +1,11 @@
+export default {
+  extensions: {
+    ts: 'module',
+  },
+  require: ['@endo/init/debug.js'],
+  nodeArguments: ['--import=tsimp/import'],
+  files: ['test/**/*.test.ts', '!test/fast-usdc/**/*.test.ts'],
+  concurrency: 1,
+  serial: true,
+  timeout: '125s',
+};
diff --git a/multichain-testing/package.json b/multichain-testing/package.json
index 4da3c7459343..1f1fd9cec8a1 100644
--- a/multichain-testing/package.json
+++ b/multichain-testing/package.json
@@ -8,7 +8,8 @@
     "lint:eslint": "eslint .",
     "lint:types": "tsc --noEmit",
     "lint-fix": "yarn lint:eslint --fix",
-    "test": "ava",
+    "test": "ava --config ava.main.config.js",
+    "test:fast-usdc": "FILE=config.fusdc.yaml ava --config ava.fusdc.config.js",
     "starship:setup": "make setup-deps setup-kind",
     "starship:install": "make install",
     "starship:port-forward": "make port-forward",
@@ -44,23 +45,6 @@
   "resolutions": {
     "axios": "1.6.7"
   },
-  "ava": {
-    "extensions": {
-      "ts": "module"
-    },
-    "require": [
-      "@endo/init/debug.js"
-    ],
-    "nodeArguments": [
-      "--import=tsimp/import"
-    ],
-    "files": [
-      "**/*.test.ts"
-    ],
-    "concurrency": 1,
-    "serial": true,
-    "timeout": "125s"
-  },
   "eslintConfig": {
     "root": true,
     "env": {
diff --git a/multichain-testing/test/fast-usdc/README.md b/multichain-testing/test/fast-usdc/README.md
new file mode 100644
index 000000000000..4d8cb0dd8e0a
--- /dev/null
+++ b/multichain-testing/test/fast-usdc/README.md
@@ -0,0 +1,14 @@
+## Start Chains
+
+Runs agoric, noble, and osmosis with hermes relayers.
+
+```sh
+# start starship with fusdc configuration
+make start FILE=config.fusdc.yaml
+```
+
+## Run Tests
+
+```sh
+yarn test:fast-usdc
+```
diff --git a/multichain-testing/test/support.ts b/multichain-testing/test/support.ts
index 2267b8134367..f02f06ca0aa6 100644
--- a/multichain-testing/test/support.ts
+++ b/multichain-testing/test/support.ts
@@ -5,7 +5,7 @@ import fse from 'fs-extra';
 import childProcess from 'node:child_process';
 import { makeAgdTools } from '../tools/agd-tools.js';
 import { type E2ETools } from '../tools/e2e-tools.js';
-import { makeGetFile, makeSetupRegistry } from '../tools/registry.js';
+import { makeGetFile, makeSetupRegistry, type UseChainFn } from '../tools/registry.js';
 import { generateMnemonic } from '../tools/wallet.js';
 import { makeRetryUntilCondition } from '../tools/sleep.js';
 import { makeDeployBuilder } from '../tools/deploy.js';
@@ -54,7 +54,16 @@ const makeKeyring = async (
 };
 
 export const commonSetup = async (t: ExecutionContext) => {
-  const { useChain } = await setupRegistry();
+  let useChain: UseChainFn;
+  try {
+    const registry = await setupRegistry({
+      config: `../${process.env.FILE || 'config.yaml'}`,
+    });
+    useChain = registry.useChain;
+  } catch (e) {
+    console.error('setupRegistry failed', e);
+    throw e;
+  }
   const tools = await makeAgdTools(t.log, childProcess);
   const keyring = await makeKeyring(tools);
   const deployBuilder = makeDeployBuilder(tools, fse.readJSON, execa);