diff --git a/SequenceAnalysis/pipeline_code/sequence_tools_install.sh b/SequenceAnalysis/pipeline_code/sequence_tools_install.sh
index feef079c7..2e0b5e79f 100755
--- a/SequenceAnalysis/pipeline_code/sequence_tools_install.sh
+++ b/SequenceAnalysis/pipeline_code/sequence_tools_install.sh
@@ -866,9 +866,9 @@ then
       install ./cutadapt-1.8.1/bin/_preamble.py ${LKTOOLS_DIR}/_preamble.py
       cp -R ./cutadapt-1.8.1/cutadapt ${LKTOOLS_DIR}/cutadapt
     else
-      $PIP_EXE install --user cutadapt==4.2
+      $PIP_EXE install --user --break-system-packages cutadapt==4.2
       $PIP_EXE show cutadapt
-      $PIP_EXE install --user pyinstaller
+      $PIP_EXE install --user --break-system-packages pyinstaller
       $PIP_EXE show pyinstaller
       ~/.local/bin/pyinstaller --onefile --clean ~/.local/bin/cutadapt
       cp ./dist/cutadapt ${LKTOOLS_DIR}/cutadapt