diff --git a/src/api/entities/AuditTrail.ts b/src/api/entities/AuditTrail.ts
index 442c1fa50..55b353d41 100644
--- a/src/api/entities/AuditTrail.ts
+++ b/src/api/entities/AuditTrail.ts
@@ -19,6 +19,7 @@ export enum AuditTrailEvents {
   UpdateDomainNames = 'UpdateDomainNames',
   UpdateAppNames = 'UpdateAppNames',
   ManageTeamMembers = 'ManageTeamMembers',
+  ChangeUserLock = 'ChangeUserLock',
 }
 
 export class AuditTrail extends BaseModel {
diff --git a/src/api/entities/User.ts b/src/api/entities/User.ts
index 77e2c53e7..8c7a083b3 100644
--- a/src/api/entities/User.ts
+++ b/src/api/entities/User.ts
@@ -63,6 +63,7 @@ export class User extends BaseModel {
   declare jobFunction: UserJobFunction;
   declare participants?: Participant[];
   declare acceptedTerms: boolean;
+  declare locked?: boolean;
   declare userToParticipantRoles?: UserToParticipantRole[];
 
   static readonly modifiers = {
@@ -85,6 +86,7 @@ export const UserSchema = z.object({
   phone: z.string().optional(),
   jobFunction: z.nativeEnum(UserJobFunction).optional(),
   acceptedTerms: z.boolean(),
+  locked: z.boolean().optional(),
 });
 
 export const UserCreationPartial = UserSchema.pick({
diff --git a/src/api/middleware/usersMiddleware.ts b/src/api/middleware/usersMiddleware.ts
index d162a6503..05626971b 100644
--- a/src/api/middleware/usersMiddleware.ts
+++ b/src/api/middleware/usersMiddleware.ts
@@ -46,6 +46,9 @@ export const enrichCurrentUser = async (req: UserRequest, res: Response, next: N
   if (!user) {
     return res.status(404).send([{ message: 'The user cannot be found.' }]);
   }
+  if (user.locked) {
+    return res.status(403).send([{ message: 'Unauthorized.' }]);
+  }
   req.user = user;
   return next();
 };
diff --git a/src/api/routers/managementRouter.ts b/src/api/routers/managementRouter.ts
index e67709ff3..2cbb4f05f 100644
--- a/src/api/routers/managementRouter.ts
+++ b/src/api/routers/managementRouter.ts
@@ -1,18 +1,32 @@
 import express, { Response } from 'express';
+import { z } from 'zod';
 
 import { isSuperUserCheck } from '../middleware/userRoleMiddleware';
+import { getAllUsersList, getUserById, updateUserLock } from '../services/managementService';
 import { ParticipantRequest } from '../services/participantsService';
-import { getAllUsersList } from '../services/usersService';
 
 const handleGetAllUsers = async (req: ParticipantRequest, res: Response) => {
   const userList = await getAllUsersList();
   return res.status(200).json(userList);
 };
 
+const handleChangeUserLock = async (req: ParticipantRequest, res: Response) => {
+  const { userId } = z.object({ userId: z.coerce.number() }).parse(req.params);
+  const { isLocked } = z.object({ isLocked: z.boolean() }).parse(req.body);
+  const user = await getUserById(userId);
+  if (req.auth?.payload?.email === user?.email) {
+    res.status(403).send([{ message: 'You cannot lock yourself.' }]);
+    return;
+  }
+  await updateUserLock(req, userId, isLocked);
+  return res.status(200).end();
+};
+
 export function createManagementRouter() {
   const managementRouter = express.Router();
 
   managementRouter.get('/users', isSuperUserCheck, handleGetAllUsers);
+  managementRouter.patch('/:userId/changeLock', isSuperUserCheck, handleChangeUserLock);
 
   return managementRouter;
 }
diff --git a/src/api/services/managementService.ts b/src/api/services/managementService.ts
new file mode 100644
index 000000000..d01682aec
--- /dev/null
+++ b/src/api/services/managementService.ts
@@ -0,0 +1,43 @@
+import { AuditAction, AuditTrailEvents } from '../entities/AuditTrail';
+import { User } from '../entities/User';
+import { getTraceId } from '../helpers/loggingHelpers';
+import {
+  constructAuditTrailObject,
+  performAsyncOperationWithAuditTrail,
+} from './auditTrailService';
+import { UserParticipantRequest } from './participantsService';
+import { findUserByEmail } from './usersService';
+
+export const getAllUsersList = async () => {
+  const userList = await User.query().where('deleted', 0).orderBy('email');
+  return userList;
+};
+
+export const getUserById = async (userId: number) => {
+  const user = await User.query().where('id', userId).first();
+  return user;
+};
+
+export const updateUserLock = async (
+  req: UserParticipantRequest,
+  userId: number,
+  isLocked: boolean
+) => {
+  const requestingUser = await findUserByEmail(req.auth?.payload.email as string);
+  const updatedUser = await User.query().where('id', userId).first();
+  const traceId = getTraceId(req);
+
+  const auditTrailInsertObject = constructAuditTrailObject(
+    requestingUser!,
+    AuditTrailEvents.ChangeUserLock,
+    {
+      action: AuditAction.Update,
+      email: updatedUser?.email,
+      locked: isLocked,
+    }
+  );
+
+  await performAsyncOperationWithAuditTrail(auditTrailInsertObject, traceId, async () => {
+    await User.query().where('id', userId).update({ locked: isLocked });
+  });
+};
diff --git a/src/api/services/usersService.ts b/src/api/services/usersService.ts
index c4bdadaaf..842a80a0d 100644
--- a/src/api/services/usersService.ts
+++ b/src/api/services/usersService.ts
@@ -74,6 +74,7 @@ export const findUserByEmail = async (email: string) => {
   const user = await User.query()
     .findOne('email', email)
     .where('deleted', 0)
+    .where('locked', 0)
     .modify('withParticipants');
 
   if (user?.participants) {
@@ -107,6 +108,7 @@ export const getAllUsersFromParticipantWithRoles = async (participant: Participa
   const usersWithParticipants = await User.query()
     .whereIn('id', participantUserIds)
     .where('deleted', 0)
+    .where('locked', 0)
     .withGraphFetched('userToParticipantRoles');
 
   return mapUsersWithParticipantRoles(usersWithParticipants, participant.id);
@@ -117,7 +119,7 @@ export const getAllUsersFromParticipant = async (participant: Participant) => {
     await UserToParticipantRole.query().where('participantId', participant.id)
   ).map((userToParticipantRole) => userToParticipantRole.userId);
 
-  return User.query().whereIn('id', participantUserIds).where('deleted', 0);
+  return User.query().whereIn('id', participantUserIds).where('deleted', 0).where('locked', 0);
 };
 
 export const sendInviteEmailToExistingUser = (
@@ -198,8 +200,3 @@ export const inviteUserToParticipant = async (
     await createUserInPortal(userPartial, participant!.id, userRoleId);
   }
 };
-
-export const getAllUsersList = async () => {
-  const userList = await User.query().where('deleted', 0).orderBy('email');
-  return userList;
-};
diff --git a/src/database/migrations/20250304185826_lock-column-users-table.ts b/src/database/migrations/20250304185826_lock-column-users-table.ts
new file mode 100644
index 000000000..482428f32
--- /dev/null
+++ b/src/database/migrations/20250304185826_lock-column-users-table.ts
@@ -0,0 +1,14 @@
+import { Knex } from 'knex';
+
+export async function up(knex: Knex): Promise<void> {
+  await knex.schema.alterTable('users', (table) => {
+    table.boolean('locked').defaultTo(false).notNullable();
+  });
+  await knex('users').update({ locked: false });
+}
+
+export async function down(knex: Knex): Promise<void> {
+  await knex.schema.alterTable('users', (table) => {
+    table.dropColumn('locked');
+  });
+}
diff --git a/src/web/App.tsx b/src/web/App.tsx
index d2a9fe4f7..644796597 100644
--- a/src/web/App.tsx
+++ b/src/web/App.tsx
@@ -6,6 +6,7 @@ import { EnvironmentBanner } from './components/Core/Banner/EnvironmentBanner';
 import { ErrorView } from './components/Core/ErrorView/ErrorView';
 import { Loading } from './components/Core/Loading/Loading';
 import { ToastContainerWrapper } from './components/Core/Popups/Toast';
+import { LockedUserView } from './components/Navigation/LockedUserView';
 import { NoParticipantAccessView } from './components/Navigation/NoParticipantAccessView';
 import { PortalHeader } from './components/PortalHeader/PortalHeader';
 import { UpdatesTour } from './components/SiteTour/UpdatesTour';
@@ -25,6 +26,9 @@ function AppContent() {
   const { participant } = useContext(ParticipantContext);
   const isLocalDev = process.env.NODE_ENV === 'development';
 
+  if (LoggedInUser?.isLocked) {
+    return <LockedUserView />;
+  }
   if (LoggedInUser?.user?.participants!.length === 0) {
     return <ErrorView message='You do not have access to any participants.' />;
   }
diff --git a/src/web/components/Navigation/LockedUserView.scss b/src/web/components/Navigation/LockedUserView.scss
new file mode 100644
index 000000000..767a6e33d
--- /dev/null
+++ b/src/web/components/Navigation/LockedUserView.scss
@@ -0,0 +1,14 @@
+.user-locked-container {
+  display: flex;
+  flex-direction: column;
+  align-items: center;
+  padding: 4.5rem 6.5rem;
+  font-size: 2rem;
+  background-color: var(--theme-background-content);
+  height: 100vh;
+
+  .no-access-text {
+    font-weight: bold;
+    margin-bottom: 0.25rem;
+  }
+}
diff --git a/src/web/components/Navigation/LockedUserView.tsx b/src/web/components/Navigation/LockedUserView.tsx
new file mode 100644
index 000000000..544d7216b
--- /dev/null
+++ b/src/web/components/Navigation/LockedUserView.tsx
@@ -0,0 +1,9 @@
+import './LockedUserView.scss';
+
+export function LockedUserView() {
+  return (
+    <div className='user-locked-container'>
+      <p className='no-access-text'>Access Forbidden.</p>
+    </div>
+  );
+}
diff --git a/src/web/components/PortalHeader/PortalHeader.scss b/src/web/components/PortalHeader/PortalHeader.scss
index e3b1187e9..115c63f20 100644
--- a/src/web/components/PortalHeader/PortalHeader.scss
+++ b/src/web/components/PortalHeader/PortalHeader.scss
@@ -97,7 +97,7 @@
     }
 
     .theme-toggle[data-state='checked'] {
-      background-color: 'black';
+      background-color: black;
     }
 
     .thumb {
diff --git a/src/web/components/UserManagement/UserManagementItem.scss b/src/web/components/UserManagement/UserManagementItem.scss
index 28659ac58..fd0e1860a 100644
--- a/src/web/components/UserManagement/UserManagementItem.scss
+++ b/src/web/components/UserManagement/UserManagementItem.scss
@@ -17,4 +17,42 @@
   .approver-name {
     margin-right: 40px;
   }
+
+  .theme-switch {
+    button {
+      all: unset;
+    }
+
+    color: var(--theme-secondary);
+    display: flex;
+    justify-content: space-between;
+    margin-top: 10px;
+    margin-bottom: 10px;
+
+    .theme-toggle {
+      width: 42px;
+      height: 25px;
+      background-color: gray;
+      border-radius: 9999px;
+      margin-left: 10px;
+      cursor: pointer;
+    }
+
+    .theme-toggle[data-state='checked'] {
+      background-color: crimson;
+    }
+
+    .thumb {
+      display: block;
+      width: 21px;
+      height: 21px;
+      background-color: white;
+      border-radius: 9999px;
+      transform: translateX(2px);
+    }
+
+    .thumb[data-state='checked'] {
+      transform: translateX(19px);
+    }
+  }
 }
diff --git a/src/web/components/UserManagement/UserManagementItem.tsx b/src/web/components/UserManagement/UserManagementItem.tsx
index e2eb57b52..1240faea1 100644
--- a/src/web/components/UserManagement/UserManagementItem.tsx
+++ b/src/web/components/UserManagement/UserManagementItem.tsx
@@ -1,12 +1,19 @@
+import * as Switch from '@radix-ui/react-switch';
+
 import { UserDTO } from '../../../api/entities/User';
 
 import './UserManagementItem.scss';
 
 type UserManagementItemProps = Readonly<{
   user: UserDTO;
+  onChangeUserLock: (userId: number, isLocked: boolean) => Promise<void>;
 }>;
 
-export function UserManagementItem({ user }: UserManagementItemProps) {
+export function UserManagementItem({ user, onChangeUserLock }: UserManagementItemProps) {
+  const onLockedToggle = async () => {
+    await onChangeUserLock(user.id, !user.locked);
+  };
+
   return (
     <tr className='user-management-item'>
       <td>{user.email}</td>
@@ -14,8 +21,18 @@ export function UserManagementItem({ user }: UserManagementItemProps) {
       <td>{user.lastName}</td>
       <td>{user.jobFunction}</td>
       <td>{user.acceptedTerms ? 'True' : 'False'}</td>
-      <td />
-      <td />
+      <td>
+        <div className='theme-switch action-cell' title='Disable User Access'>
+          <Switch.Root
+            name='user-locked'
+            checked={user.locked}
+            onCheckedChange={onLockedToggle}
+            className='theme-toggle clickable-item'
+          >
+            <Switch.Thumb className='thumb' />
+          </Switch.Root>
+        </div>
+      </td>
     </tr>
   );
 }
diff --git a/src/web/components/UserManagement/UserManagementTable.tsx b/src/web/components/UserManagement/UserManagementTable.tsx
index c807fe409..85de69aa1 100644
--- a/src/web/components/UserManagement/UserManagementTable.tsx
+++ b/src/web/components/UserManagement/UserManagementTable.tsx
@@ -13,6 +13,7 @@ import './UserManagementTable.scss';
 
 type UserManagementTableProps = Readonly<{
   users: UserDTO[];
+  onChangeUserLock: (userId: number, isLocked: boolean) => Promise<void>;
 }>;
 
 function NoUsers() {
@@ -23,7 +24,7 @@ function NoUsers() {
   );
 }
 
-function UserManagementTableContent({ users }: UserManagementTableProps) {
+function UserManagementTableContent({ users, onChangeUserLock }: UserManagementTableProps) {
   const initialRowsPerPage = 25;
   const initialPageNumber = 1;
 
@@ -96,14 +97,13 @@ function UserManagementTableContent({ users }: UserManagementTableProps) {
             <SortableTableHeader<UserDTO> sortKey='lastName' header='Last Name' />
             <SortableTableHeader<UserDTO> sortKey='jobFunction' header='Job Function' />
             <th>Accepted Terms</th>
-            <th>Delete Action Here</th>
-            <th>Lock Action Here</th>
+            <th className='action'>Locked</th>
           </tr>
         </thead>
 
         <tbody>
           {pagedRows.map((user) => (
-            <UserManagementItem key={user.id} user={user} />
+            <UserManagementItem key={user.id} user={user} onChangeUserLock={onChangeUserLock} />
           ))}
         </tbody>
       </table>
diff --git a/src/web/contexts/CurrentUserProvider.tsx b/src/web/contexts/CurrentUserProvider.tsx
index f61d1b9d5..da1c1bb2e 100644
--- a/src/web/contexts/CurrentUserProvider.tsx
+++ b/src/web/contexts/CurrentUserProvider.tsx
@@ -26,10 +26,11 @@ function CurrentUserProvider({ children }: Readonly<{ children: ReactNode }>) {
     setIsLoading(true);
     try {
       const profile = await keycloak.loadUserProfile();
-      const user = await GetLoggedInUserAccount();
+      const { user, isLocked } = await GetLoggedInUserAccount();
       SetLoggedInUser({
         profile,
         user,
+        isLocked,
       });
     } catch (e: unknown) {
       if (e instanceof Error) throwError(e);
diff --git a/src/web/screens/manageUsers.tsx b/src/web/screens/manageUsers.tsx
index 638858a39..5d6b948b3 100644
--- a/src/web/screens/manageUsers.tsx
+++ b/src/web/screens/manageUsers.tsx
@@ -1,10 +1,11 @@
 import { Suspense } from 'react';
+import { useRevalidator } from 'react-router-dom';
 import { defer, useLoaderData } from 'react-router-typesafe';
 
 import { Loading } from '../components/Core/Loading/Loading';
 import { ScreenContentContainer } from '../components/Core/ScreenContentContainer/ScreenContentContainer';
 import UserManagementTable from '../components/UserManagement/UserManagementTable';
-import { GetAllUsers } from '../services/userAccount';
+import { ChangeUserLock, GetAllUsers } from '../services/userAccount';
 import { AwaitTypesafe } from '../utils/AwaitTypesafe';
 import { RouteErrorBoundary } from '../utils/RouteErrorBoundary';
 import { PortalRoute } from './routeUtils';
@@ -16,6 +17,12 @@ const loader = () => {
 
 function ManageUsers() {
   const data = useLoaderData<typeof loader>();
+  const reloader = useRevalidator();
+
+  const onChangeUserLock = async (userId: number, isLocked: boolean) => {
+    await ChangeUserLock(userId, isLocked);
+    reloader.revalidate();
+  };
 
   return (
     <>
@@ -24,7 +31,7 @@ function ManageUsers() {
       <ScreenContentContainer>
         <Suspense fallback={<Loading message='Loading users...' />}>
           <AwaitTypesafe resolve={data.userList}>
-            {(users) => <UserManagementTable users={users} />}
+            {(users) => <UserManagementTable users={users} onChangeUserLock={onChangeUserLock} />}
           </AwaitTypesafe>
         </Suspense>
       </ScreenContentContainer>
diff --git a/src/web/services/userAccount.ts b/src/web/services/userAccount.ts
index 7bf54cd2e..62f944c54 100644
--- a/src/web/services/userAccount.ts
+++ b/src/web/services/userAccount.ts
@@ -10,6 +10,7 @@ import { backendError } from '../utils/apiError';
 export type UserAccount = {
   profile: KeycloakProfile;
   user: UserWithParticipantRoles | null;
+  isLocked?: boolean;
 };
 
 export type InviteTeamMemberForm = {
@@ -20,17 +21,23 @@ export type InviteTeamMemberForm = {
   userRoleId?: number;
 };
 
+export type LoggedInUser = {
+  user: UserWithParticipantRoles | null;
+  isLocked?: boolean;
+};
+
 export type UpdateTeamMemberForm = Omit<InviteTeamMemberForm, 'email'>;
 
 export type UserPayload = z.infer<typeof UserCreationPartial>;
 
-export async function GetLoggedInUserAccount(): Promise<UserWithParticipantRoles | null> {
+export async function GetLoggedInUserAccount(): Promise<LoggedInUser> {
   try {
     const result = await axios.get<UserWithParticipantRoles>(`/users/current`, {
-      validateStatus: (status) => [200, 404].includes(status),
+      validateStatus: (status) => [200, 403, 404].includes(status),
     });
-    if (result.status === 200) return result.data;
-    return null;
+    if (result.status === 403) return { user: null, isLocked: true };
+    if (result.status === 200) return { user: result.data };
+    return { user: null };
   } catch (e: unknown) {
     throw backendError(e, 'Could not get user account');
   }
@@ -113,3 +120,11 @@ export async function GetAllUsers() {
     throw backendError(e, 'Unable to get user list.');
   }
 }
+
+export async function ChangeUserLock(userId: number, isLocked: boolean) {
+  try {
+    return await axios.patch(`/manage/${userId}/changeLock`, { userId, isLocked });
+  } catch (e: unknown) {
+    throw backendError(e, 'Unable to update user lock status.');
+  }
+}