An application of two-stage design for a multi-city analysis in environmental epidemiology. The application partly reproduces the results of an analysis of the excess risk attributable to non-optimal outdoor temperature in a multi-country dataset, published in:
Gasparrini A, Guo Y, Hashizume M, Lavigne E, Zanobetti A, Schwartz J, Tobias A, Tong S, Rocklöv J, Forsberg B, Leone M, De Sario M, Bell ML, Guo YLL, Wu CF, Kan H, Yi SM, de Sousa Zanotti Stagliorio Coelho M, Saldiva PH, Honda Y, Kim H, Armstrong B. Mortality risk attributable to high and low ambient temperature: a multicountry observational study. The Lancet. 2015;386(9991):369-375. [freely available here]
The code:
- regEngWales stores the daily time series data from 10 locations corresponding to regions of England and Wales in the period 1993--2006
- attrdl.R creates the function for computing the attributable risk measures
- attrdl.pdf is the help page for the function
attrdl() - the numbered files from 00.prepdata.R to 05.plots.R, reproduce the results of an example with the subset of data
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