Can mixcr do some post-analysis based on processed data of 10x Genomics TCR sequence

[linqy-immune]

Dear developers and users of MiXCR,
Hello!
I'm a big fan of MiXCR and have already analyzed some data by this software. Recently, I want to do some down-stream TCR analysis by MiXCR based on a group of data downloaded from public websites. The group pf data is processed by 10x Genomics and the headlines of each file are "multi_chain TRA_1_cdr3 TRA_2_cdr3 TRB_1_cdr3 TRB_2_cdr3 TRA_1_junction_ins TRA_2_junction_ins TRB_1_junction_ins TRB_2_junction_ins TRA_1_expr TRA_2_expr TRB_1_expr TRB_2_expr TRA_1_v_gene TRA_2_v_gene TRB_1_v_gene TRB_2_v_gene TRA_1_d_gene TRA_2_d_gene TRB_1_d_gene TRB_2_d_gene TRA_1_j_gene TRA_2_j_gene TRB_1_j_gene TRB_2_j_gene TRA_1_c_gene TRA_2_c_gene TRB_1_c_gene TRB_2_c_gene TRA_1_cdr3_nt TRA_2_cdr3_nt TRB_1_cdr3_nt TRB_2_cdr3_nt has_tcr chain_pairing clonotype clonotype_size clonal_expansion". The raw data is not provided and it seems that I can only analyzed by these processed data.
Is there any method to analyze these txt files for overlap and V/J segment usage? Could you please give me some advice and I would appreciate it.
Thanks and best regards,
Linqy

[mizraelson]

Hi Linqy,
MiXCR only allows post-analysis if the data was processed with MiXCR from raw FASTQ files. A common solution would be to use Python or R, where you can perform virtually any type of analysis.