diff --git a/reports/CSL.Rmd b/reports/CSL.Rmd index d86e5eb..7b649ef 100644 --- a/reports/CSL.Rmd +++ b/reports/CSL.Rmd @@ -84,7 +84,7 @@ hpo_ids_extended <- unlist(hpo_ids_list) |> unique() ### Import phenotype-cell type association results -Next, I imported the results of our phenotype-cell type association +Next, we imported the results of our phenotype-cell type association analysis. This analysis was performed using the `MSTExplorer` package and the results are stored in a data.table. @@ -102,7 +102,7 @@ p2g <- HPOExplorer::load_phenotype_to_genes() ## Prioritise targets -We developed a pipeline to help filter down our results to identif the +We developed a pipeline to help filter down our results to identify the promise promising gene targets for the most severe phenotypes. It includes a number of different steps, including filtering on cell type specific gene expression and the evidence supporting the causal diff --git a/reports/CSL.html b/reports/CSL.html index a26a028..0666947 100644 --- a/reports/CSL.html +++ b/reports/CSL.html @@ -76823,7 +76823,7 @@

Rare Disease Celltyping

CSL Areas of Interest

Brian M. Schilder


-Updated: Mar-20-2024
+Updated: Mar-21-2024

@@ -76892,7 +76892,7 @@

Import CSL areas of interest

Import phenotype-cell type association results

-

Next, I imported the results of our phenotype-cell type association +

Next, we imported the results of our phenotype-cell type association analysis. This analysis was performed using the MSTExplorer package and the results are stored in a data.table.

results <- MSTExplorer::load_example_results()
@@ -76908,7 +76908,7 @@ 

Import phenotype-cell type association results

Prioritise targets

-

We developed a pipeline to help filter down our results to identif +

We developed a pipeline to help filter down our results to identify the promise promising gene targets for the most severe phenotypes. It includes a number of different steps, including filtering on cell type specific gene expression and the evidence supporting the causal